Optimal - The Blog

April 15, 2024

Optimal DX Throwback 1981: Magnesium Deficiency

HOW MANY OF THESE MANIFESTATIONS ARE RECOGNIZED BY MODERN MEDICINE AS MAGNESIUM DEFICIENCY TODAY?

  • Magnesium deficiency can arise from inadequate dietary intake during specific life stages (early childhood, pregnancy, lactation) or due to increased bodily demands.
  • Other causes include excessive magnesium loss due to gastrointestinal malabsorption, kidney issues from diuretic use, or conditions like alcoholism that combine inadequate intake and increased loss.
  • Symptoms of magnesium deficiency vary widely and can appear gradually or suddenly, ranging from non-specific signs (often overshadowed by the primary disease) to severe manifestations such as neuromuscular hyperactivity (tremors, convulsions), psychiatric disturbances, cardiac arrhythmias, and sudden death.
  • Magnesium deficiency often presents with associated mineral imbalances, including hypocalcemia and hypokalemia, which require magnesium supplementation to resolve.
  • Treatment involves magnesium administration, with initial higher doses followed by maintenance dosing. In emergencies like severe convulsions or cardiac arrhythmias, immediate magnesium sulfate injections may be necessary.
  • Managing magnesium deficiency in patients with renal insufficiency requires careful dosing and frequent monitoring to avoid complications, as complete magnesium repletion typically occurs slowly.

Reference

Flink, E B. “Magnesium deficiency. Etiology and clinical spectrum.” Acta medica Scandinavica. Supplementum vol. 647 (1981): 125-37. doi:10.1111/j.0954-6820.1981.tb02648.x
 

Want to Learn More?

Click below to learn more about Magnesium, health consequences, the ODX ranges, etc.
 

Magnesium: Why Standard Ranges Are Suboptimal

Magnesium Deficiency Can Break Your Heart

Mineral Biomarkers: Serum Magnesium

Mineral Biomarkers: RBC Magnesium

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