Optimal - The Blog
April 9, 2024
Atherosclerosis is a condition where plaque builds up inside the arteries, leading to reduced blood flow and oxygen supply. It can lead to serious health problems, including heart attacks and strokes.
The development of atherosclerosis involves several stages, starting with the oxidation of low-density lipoprotein (LDL) in the artery walls, which attracts macrophages that turn into foam cells, forming fatty streaks. These streaks can grow into larger plaques, which can eventually rupture, leading to blood clots and blocked arteries.
Key factors contributing to atherosclerosis include inflammation, endothelial dysfunction, and the modification of LDL cholesterol.
Various biomarkers can indicate the progression of atherosclerosis, such as oxidized LDL, small dense LDL particles, lipoprotein(a), and C-reactive protein. These biomarkers help in understanding the inflammatory and oxidative processes involved in plaque formation and progression.
Progression of Atherosclerosis
Preventing and potentially reversing atherosclerosis involves maintaining a healthy lifestyle, including a diet rich in antioxidants from fruits, vegetables, herbs, spices, nuts, and seeds. It's also important to avoid highly processed foods, manage stress, get enough sleep, maintain healthy social relationships, and minimize exposure to pollution, cigarette smoke, radiation, etc.
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