Insulin-like growth factor-1 (IGF-1) is a peptide crucial for regulating the effects of growth hormone throughout the body.
While blood levels of IGF-1 mirror circulating growth hormone levels, they are more stable. Low IGF-1 levels can indicate growth hormone deficiencies, malnutrition, liver disease, or certain chronic diseases. On the contrary, high levels might signal conditions like acromegaly, gigantism, or obesity, and are linked to an increased risk for several cancers.
Monitoring IGF-1 is particularly vital as it can aid in assessing growth abnormalities and, in adults, factors like loss of muscle or bone mass, increased adiposity, and cognitive decline.
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