Optimal - The Blog

December 26, 2024

Your Brain Can Really Score with These Lifestyle Changes

The most common age-related brain disorders worldwide are stroke, dementia, and late-life depression, which is associated with cognitive decline. These conditions share risk factors that can be controlled, including physical activity, nutrition, and tobacco smoking.

Based on these modifiable factors, a Brain Care Score (BCS) can help you gauge your brain health and risk of common brain disorders (Singh 2024).

The BCS results range from 0-21 and are based on:

4 physical components

  • Blood pressure
  • Hemoglobin A1c
  • Cholesterol
  • Body Mass Index (BMI)

5 lifestyle elements

  • Nutrition
  • Alcohol intake
  • Smoking
  • Aerobic activities
  • Sleep

3 social-emotional factors

  • Stress
  • Relationships
  • Purpose in life

Data gathered from over 400,000 participants in the UK biobank study found that each 5-point increase in baseline BCS score was associated with a 33% reduced risk of late-life depression and a 27% reduced risk of combined outcomes, including dementia, late-life depression, and stroke. Optimal results based on BCS criteria include (Singh 2024):

  • Blood pressure below 120/80 mmHg
  • Hemoglobin A1C below 5.7%
  • Total cholesterol below 190 mg/dL (4.92 mmol/L)
  • BMI between 18.5 and 25 kg/m2
  • 3 or more of the following:
    • 5 servings of fruit and vegetables per day
    • 2 servings of lean protein per day
    • 3 or more servings of whole grains per day
    • Less than 1,500 mg of sodium per day
    • Less than 36 ounces of sugar-sweetened beverages (soda, juice, etc.) per week
  • Alcohol intake: 0-1 drinks per week
  • Tobacco smoking: Never smoked or quit more than a year ago
  • Aerobic activity: At least 150 minutes of moderate physical activity (ex. walking) or 75 minutes of high-intensity physical activity per week
  • Sleep: 7-8 hours per night
  • Stress: Manageable levels of stress that rarely make it difficult to function
  • Social relationships: At least 2 people besides a spouse or children, that you feel close to and could discuss private matters with or call upon to help
  • Meaning in life: You generally feel that your life has meaning and/or purpose

Brain Care Score Questionnaire

Optimal Takeaways and key actions to improve your BCS (Mass General)

  • Control your blood pressure
    • Only ~25% of adults with high blood pressure have it under control
    • Controlling blood pressure can dramatically reduce your risk of dementia and stroke
    • Maintain a healthy weight, minimize sodium from processed foods, be active, e.g., walk, dance, or bike regularly, use weight lifting to build muscle, limit alcohol intake to 0-1 drink per day, and address stress with deep breathing or meditation to control stress hormones that can increase blood pressure.
    • Avoid overeating and other unhealthy habits
  • Adopt a Mediterranean-style diet and include:
    • More leafy greens, at least 1 cup raw or a half cup cooked daily
    • Colorful fruits & veggies, e.g., avocadoes, berries, blueberries, broccoli, eggplant, and red peppers
    • Extra virgin olive oil
    • Seafood high in omega-3 EPA and DHA e.g., wild salmon, sardines, cod, mussels, and oysters
    • Nuts, seeds, and beans/legumes, aim for a total of one half to one whole cup daily, e.g., almonds, cashews, walnuts, pumpkin seeds, black beans, and lentils
    • Spices and herbs, e.g., cinnamon, cloves, nutmeg, turmeric, ginger, and saffron
    • Fermented foods, e.g., buttermilk, yogurt, curd, kefir, kombucha, and kimchi
    • Dark chocolate
  • Avoid alcohol and smoking
  • Exercise
    • At least 150 minutes per week but set reasonable goals for where you are at the moment
  • Get quality sleep
    • Prioritize sleep, using a sleep diary to evaluate your sleep schedule and how it may affect your daytime alertness
    • Maintain a comfortable sleep environment and be consistent with bedtime and number of hours set aside for sleep
    • Avoid reading, working, and screen time in bed if sleep is suboptimal
    • Avoid alcohol, caffeine, and other stimulants within six hours of bedtime
    • Try something relaxing before bed, such as a hot bath or mindfulness practice
  • Reduce stress
    • Meditation or relaxation techniques can help control your response to stress and minimize its negative effects
    • Self-reflection and evaluating your thoughts, feelings, and behaviors can help manage stress and improve brain health
  • Build healthy relationships
  • Learn new things
  • Strive for meaning and purpose in life

The Sustainable Mediterranean Diet

Source: Serra-Majem, Lluís et al. “Updating the Mediterranean Diet Pyramid towards Sustainability: Focus on Environmental Concerns.” International journal of environmental research and public health vol. 17,23 8758. 25 Nov. 2020, doi:10.3390/ijerph17238758 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license

 

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References

Singh, Sanjula D et al. “The predictive validity of a Brain Care Score for late-life depression and a composite outcome of dementia, stroke, and late-life depression: data from the UK Biobank cohort.” Frontiers in psychiatry vol. 15 1373797. 23 Jul. 2024, doi:10.3389/fpsyt.2024.1373797 This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).

Massachusetts General Hospital. Interested in improving your McCance Brain Care Score? https://www.massgeneral.org/neurology/mccance-center/research/brain-care-now

McCance Brain Care Score. https://www.massgeneral.org/assets/mgh/pdf/neurology/mccance-center/brain-care-score.pdf

NPR. You can reduce your risk of dementia. Here's how to get started. Nov25 2024. https://www.npr.org/sections/shots-health-news/2024/11/22/nx-s1-5050956/health-brain-dementia-sleep-diet-alzheimers

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