Sex Hormone-Binding globulin (SHBG) is primarily produced in the liver and plays a pivotal role in transporting sex hormones in the blood. Disturbances in liver function can result in altered SHBG levels.
A decrease in SHBG is linked to cardiometabolic dysfunction, inflammation, PCOS, and certain cancers, while elevated levels can be associated with hyperthyroidism, cardiovascular disease, malnutrition, and symptomatic hypogonadism.
Low levels of SHBG are also associated with conditions like hypothyroidism, metabolic syndrome, and cardiovascular diseases. Conversely, high SHBG levels can hint at possible risks for prostate cancer and cardiovascular issues.
Balancing SHBG levels is essential for maintaining various physiological functions.
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