White blood cells (WBCs) are critical for immune function and inflammation response. Aging is associated with a chronic inflammatory state known as "inflammaging," which can elevate WBC counts, indicating systemic inflammation.
Elevated WBCs are linked to cognitive decline and neurodegenerative diseases like Alzheimer's and Parkinson's, as they trigger central nervous system immune responses.
High WBC counts are also strong predictors of biological age, correlating with increased mortality, cardiovascular risk, and overall poor health outcomes. Managing WBC levels may be key to improving longevity and cognitive health.
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