Parathyroid hormone (PTH) is responsible for regulating calcium, phosphorus, and magnesium levels in the blood and is instrumental in activating vitamin D in the kidney.
Low PTH levels can arise from causes like parathyroid gland damage, metabolic dysfunction, and certain diseases such as Graves' disease and DiGeorge syndrome, or from medications like propranolol and cimetidine.
Conversely, elevated PTH levels can result from hypocalcemia, certain tumors, hyperparathyroidism, and conditions like chronic renal failure or specific cancers.
Medications such as steroids, lithium, and anticonvulsants can also increase PTH levels. It's vital to monitor PTH levels as imbalances, even within the standard range, may have metabolic consequences and can indicate cardiovascular risk.
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