Holotranscobalamin (HoloTC) is a complex of vitamin B12 that our bodies can readily use. It's a sensitive marker that can help detect early B12 deficiency, though it should be used alongside other markers for a comprehensive picture.
Low HoloTC can signal B12 insufficiency and is associated with several health conditions, such as neuropathy and vegetarianism, while high HoloTC could indicate anorexia nervosa or liver cell damage.
If your HoloTC is below a certain level, it's a good idea to check for B12 insufficiency. Remember, this is a specific type of vitamin B12 testing that provides additional information beyond standard B12 tests.
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