FSH is Important in Men as Well

Follicle-stimulating hormone (FSH) is a glycoprotein produced by the pituitary gland, affecting male reproductive organs and sperm production.

Low levels of FSH in males may be indicative of pituitary or hypothalamic dysfunction, negatively affecting sperm quality, while elevated levels are linked to pituitary adenoma, unresponsive gonads, and issues with artificial reproductive techniques.

A specific study found that men with higher FSH levels failed sperm retrieval for artificial reproductive purposes, suggesting a damaging effect on seminiferous tubules.

Additionally, higher FSH levels have been associated with an increased risk of castration-resistant prostate cancer (CRPC) in men undergoing androgen deprivation therapy, with a retrospective study highlighting a specific threshold for FSH levels related to CRPC development.

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