Trimethylamine N-Oxide (TMAO) is a compound linked to increased cardiovascular risk and insulin resistance. It is produced in the liver from trimethylamine (TMA). TMA is synthesized by gut bacteria from compounds found in food.
Factors like diet, gut health, and liver function influence TMAO levels. Diets high in fat and protein tend to increase TMAO, while plant-based diets may reduce it.
Dysbiosis, an imbalance in gut bacteria, can elevate TMAO production, and some natural products may help inhibit its formation.
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