Dihydrotestosterone (DHT) is Testosterone on Steroids

Dihydrotestosterone (DHT) is the most potent androgen hormone. It is primarily synthesized from testosterone and plays a vital role in promoting masculine characteristics and development.

In older men, higher DHT levels were linked to a lower risk of ischemic heart disease and overall mortality, whereas in a study of pre- and postmenopausal women with severe depression, higher DHT levels were observed. Unlike testosterone, DHT is not metabolized to estrogen, and its physiological role in women is less understood.

Low levels of DHT in men are associated with increased risks of ischemic heart disease, stroke, insulin resistance, metabolic syndrome, diabetes, and cognitive decline.

High levels of DHT may be seen in men undergoing testosterone therapy and in women with conditions like PCOS and hirsutism.

Monitoring DHT levels can be crucial for clinical assessment, as altering levels may have significant health implications.

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