LDL Particle Number Goes Beyond LDL Cholesterol

Although the focus of cardiovascular disease risk assessment in the past has been the amount of cholesterol carried by the low-density lipoprotein (LDL) carrier in the blood, research reveals that the LDL particle number is an even more important factor to address.

An elevated LDL particle number (LDL-P) is a better predictor of cardiovascular risk than LDL or non-HDL cholesterol levels. A higher LDL-P is associated with systemic inflammation, insulin resistance, high triglycerides, and small LDL particles that are more likely to become oxidized and cause atherosclerosis and heart disease. 

A healthy diet, avoiding trans-fats, maintaining a healthy weight, and regular exercise can help lower LDL particle number.

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