Optimal - The Podcast: Episode 5

Optimal - The Podcast: Episode 5: The HOMA2 Calculator in Clinical Practice - an Interview with Dr. Brad Rachman

Dr. Dicken Weatherby

This is a must-watch interview for anyone assessing and treating blood sugar dysregulation in their clinic. Dr. Brad Rachman of the Rachman Clinic shares his 10+ years of experience of using the HOMA2 calculator in his clinical practice. A must-have tool to uncover early stage Insulin Resistance and other dysfunctions of blood sugar regulation. This tool has been built into the ODX Software application.

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Episode Highlights:

(00:00) A brief intro on what Dr. Brad Rachman’s work

(00:01:23) Dr. Rachman’s process for taking someone through the diagnostics journey

(00:08:10) The epidemic of blood sugar dysregulation

(00:12:09) Biomarkers of Blood Sugar Dysregulation and the HOMA2 Calculator

(00:16:34) Nuts and bolts basics of glucose metabolism

(00:20:00) Elevated glucose as a sign that regulation is off and the effects of this

(00:21:38) HOMA2 ranges

(00:26:38) Dr. Rachman’s Blood Sugar Regulation Assessment Matrix: Early Insulin Resistance

(00:29:06) Why Dr. Rachman never uses fasting insulin to calculate HOMA2

(00:32:08) Dr. Rachman’s Blood Sugar Regulation Assessment Matrix: Late Insulin Resistance

(00:33:06) Dr. Rachman’s Blood Sugar Regulation Assessment Matrix: Type 2 Diabetes

(00:34:35) Dr. Rachman’s Blood Sugar Regulation Assessment Matrix: Reactive Hypoglycemia

(00:41:14) Dr. Rachman’s Blood Sugar Regulation Assessment Matrix: Type 3C Diabetes

(00:44:10) Dr. Raschman discusses his insights on what to do when presented with patients on this matrix

Dr. Brad Rachman's Blood Sugar Dysregulation Assessment Matrix

This is the matrix Dr. Rachman goes over in the interview above. It takes full advantage of the results generated by the HOMA2 calculator (%S, %B, and HOMA-IR). Dr. Rachman explains that he wouldn't be able to assess for these without the indices generated by the HOMA2 calculator. 

This Matrix is used with permission from Dr. Brad Rachman © Brad Rachman

Where to Reach Dr. Rachman:

Genova Diagnostics LinkedIn

Dr. Brad Rachman LinkedIn

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The ODX HOMA2 Series

1. HOMA2 part 1 - The HOMA2 Calculator: An Important Series of Indices for Gauging Insulin Resistance
2. HOMA2 part 2 - HOMA2 - %B: An Index For Gauging the Beta Cell Output of Insulin from the Pancreas
3. HOMA2 part 3 - HOMA2 - %S: An Index For Assessing Cellular Sensitivity to Insulin
4. HOMA2 part 4 - HOMA2 - IR: An Index For Assessing the Degree of Insulin Resistance
5. Bonus - QUICKI – An Additional Index for Assessing Insulin Resistance in Our Patients