Creatinine, a key indicator of kidney function and muscle metabolism, rises as the kidneys' ability to filter waste decreases.
As we age, the kidneys undergo structural changes, including reduced volume and increased tissue accumulation, leading to impaired filtration and higher creatinine levels. Elevated creatinine is associated with chronic kidney disease (CKD), which can cause vascular damage, oxidative stress, and cognitive decline.
Research shows that declining kidney function correlates with poorer cognitive performance and brain atrophy.
Monitoring creatinine levels is crucial for assessing biological age and predicting longevity, emphasizing the importance of kidney health for overall well-being and aging.
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