Fibrinogen is a substance that helps your blood clot, and without it, you can have bleeding problems. However, too much can contribute to chronic conditions, including heart disease, peripheral artery disease, and stroke.
Elevated levels are associated with smoking, pollution, inflammation, acute infection, critical illness, and vascular disease and mortality. Persistently high levels can be associated with other inflammatory markers and increase the risk of dying of heart disease.
Maintaining an optimal omega-3 fatty acid level in the blood can reduce elevations in fibrinogen. Research indicates that supplementation with fish oil sources of Omega-3 EPA and DHA can successfully reduce the fibrinogen response to pollution. However, omega-3 alpha-linolenic acid, the plant-based precursor to EPA and DHA did not.
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